Rapidly develop your own clinically relevant oncology tumor models with lentiviral vectors from Imanis – featuring the transgenes you need, the QC data to show it, and the scientific team to back it.
Imanis’s lentiviral vectors express transgenes that are well-suited for a range of oncology studies. Our reporter vectors encode fluorescent proteins or bright firefly luciferase, which is ideal for longitudinal studies tracking tumor growth, metastasis, and therapeutic efficacy in living animals. We also have lentiviral vectors that encode tumor antigens of interest, including BCMA, CD19, B7H3, and EGFR, which are popular targets for immunotherapies in particular.
Efficiently delivered, highly expressed
To accelerate in vitro and in vivo research
All our lentiviral vectors undergo rigorous quality control testing to ensure accurate titer, sterility, and robust transgene expression. To increase biosafety, all are self-inactivating.
Get answers to common questions about lentiviral vectors
Our lentiviral vectors use the spleen focus-forming virus (SFFV) promoter to drive transgene expression. Not only is the SFFV promoter highly and constitutively active in vitro, but it is not prone to silencing in mice, as can be observed with other strong promoters.
Our off-the-shelf lentiviral vectors are second generation self-inactivating vectors. We have the capability to produce custom third-generation lentiviral vectors upon request.
Lentiviral vectors are powerful tools for engineering immortalized cell lines because they stably integrate into the host cell genome. This means that transgenes are retained and replicated with the cells. They are also easy to use and highly efficient.
Don’t see what you need in our catalog? Our scientific team engineers cell lines, viral vectors, and assays and provides as much characterization data as you need to move forward with confidence.
